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About approaches on mathematical simulation of biosensor and immunosensor dynamic systems

Martsenyuk V.1, Sverstiuk A.2
1 I.Ya. Horbachevsky Ternopil State Medical University
2 Ternopil Medical State University named I. Gorbachevsky

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UDC: 602.1:519.85:53.082.9:616-07
Publication Language: Ukrainian
Stuc. intelekt. 2018; 23(2):94-102

Abstract: The mathematical models of biosensory and immunosensory dynamical systems in the form of differential equations in partial derivatives are considered in this paper. Models for optimizing the development of biosensors, a biosensor model in cylindrical coordinates, based on the use of Michaelis-Menten kinetics and reaction-diffusion equations are proposed. A model of the immunosensor in the form of lattice partial differential equations with delay was developed. The construction of the model is based on a number of biological assumptions about the interaction of colonies of antigens and antibodies, as well as the diffusion of antigens. For the description of discrete spaces in the space of the colonies, localized in the corresponding pixels, the apparatus of lattice differential equations is used.

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